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Symbol
Name
ID
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1
MGI:95412
Phenotype annotations related to liver/biliary system
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Extrahepatic cholestasis
Jaundice
Neoplasm of the liver
Disease(s) Associated with ERCC1
pancreatic cancer

Mouse Phenotypes
increased hepatocyte apoptosis
decreased hepatocyte proliferation
increased liver triglyceride level
abnormal hepatocyte morphology
hepatic steatosis
liver degeneration
abnormal liver physiology
decreased liver function
Availability Mouse Genotype
Ercc1tm1Dwm/Ercc1tm1Dwm
Ercc1tm1Jhjh/Ercc1tm1Jhjh
Ercc1tm2Jhjh/Ercc1tm2Jhjh
Ercc1tm1Dwm/Ercc1+
Ercc1tm1Jhjh/Ercc1tm2Jhjh

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory