Symbol Name ID |
Ercc1
excision repair cross-complementing rodent repair deficiency, complementation group 1 MGI:95412 |
Darker colors indicate more annotations |
Human Phenotypes | Hepatosplenomegaly |
Extrahepatic cholestasis |
Jaundice |
Neoplasm of the liver |
Disease(s) Associated with ERCC1 | ||||
pancreatic cancer |
Mouse Phenotypes | increased hepatocyte apoptosis |
decreased hepatocyte proliferation |
increased liver triglyceride level |
abnormal hepatocyte morphology |
hepatic steatosis |
liver degeneration |
abnormal liver physiology |
decreased liver function |
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Availability | Mouse Genotype | ||||||||
Ercc1tm1Dwm/Ercc1tm1Dwm | |||||||||
Ercc1tm1Jhjh/Ercc1tm1Jhjh | |||||||||
Ercc1tm2Jhjh/Ercc1tm2Jhjh | |||||||||
Ercc1tm1Dwm/Ercc1+ | |||||||||
Ercc1tm1Jhjh/Ercc1tm2Jhjh |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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